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August 2010  
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TRANSASIA BIO-MEDICALS LTD

Sysmex XT 4000i

Transasia Bio-Medicals Ltd, India's leading IVD company and the leader in the hematology market segment, has always been on the forefront in bringing high quality, state of the art technological advances to the end users at competitive prices, so as to ensure that the healthcare providers can offer highly reliable and affordable diagnostic solutions to the patient population. Transasia has always focused to leverage the extensive scientific and R&D capabilities of Sysmex, and this strategic partnership has enabled Transasia to be the undisputed choice amongst the medical fraternity while choosing their hematology analyzers. This coupled with around 58 service centers and more than 100 service engineers has enabled Transasia to successively build happy relationships with more than 20,000 satisfied customers across India.

Since the beginning of the launch of Sysmex 5 part analyzers in India, Transasia has been continuously focusing on bringing the latest technological advances to the healthcare providers in terms of upgrading the number of parameters available and incorporation of special reportable parameters to enable better diagnostic and monitoring capabilities. Continuing the same trend in 2010, Transasia has launched the Sysmex XT 4000i, a fully automated Fluroscence Flow Cytometry based, high end 6 part differential haematology analyzer also incorporated with two special softwares for enumerating Ret-He and IG . The analyzer also reports body fluid, reticulocyte count and IRF (Immature reticulocyte fraction) for evaluation of bone marrow erythropoietic activity.

Features of XT 4000i

  • Fully automated fluorescence flow cytometry based 6-part differential hematology analyzer.
  • Features four discrete analysis modes: CBC, CBC+DIFF, CBC+RET, CBC+DIFF+RET.
  • Parameters :WBC, RBC, HGB, HCT, MCV, MCH, MCHC, PLT, NEUT %, LYMPH %, MONO%, EOS %, BASO %, NEUT #, LYMPH #, MONO #, EOS #, BASO #, RET %, RET #, RDW-SD, RDW-CV, PDW, MPV, PCT, P-LCR, HFR, MFR, LFR, IRF, PLT -O, PCT, Ret -He , IG#, IG%.
  • RBC & Plt Histograms, and 5 Scattergrams.
  • Up to 100 samples per hour in all the discrete analysis modes.
  • Multichannel analysis.
  • Comprehensive information processing system and data storage.
  • Semiconductor laser has lower power consumption, higher stability, and longer life thus cutting down on maintenance cost.
  • Fully automated Reticulocytes analysis with Flouroscence Flow cytometry, no pre treatment and faster reporting time of just 60 seconds.
  • Platelet count switching algorithm between impedence and optical methods for reliable and accurate platelet counts.
  • Q Flagging systems to further reduce smear reviews and extensive QC features like X Bar M and LJ Plots, Delta checks and Online QC options etc.

The Sysmex XT4000i, approved by the US FDA, has the latest reportable parameters like IG Counts which help in the early diagnosis of sepsis and inflammation. The rapid and reliable enumeration of Immature Granulocytes helps facilitate detection and monitor treatment.

Measurement of immature granulocyte can be used as a predictor of infection or positive blood culture and compared the results with total WBC count and absolute neutrophil count (ANC).

The presence of immature granulocytes (IG) in peripheral blood is potentially important information indicating enhanced bone marrow activation.
The quantification of immature granulocytes is routinely done by visual microscopy, which is a labour intensive and time consuming task. The traditional visual 100-cell differential has further disadvantages: due to the small number of cells counted it shows high imprecision, low reproducibility and a relatively wide inter-examiner variability. Thus, there is need for a reliable automated quantitative IG count.

Also, there are new diagnostic parameters like IRF for erythropoietic functions and Ret He. Haematologic indices are the new gold standard to assess Iron deficiency and to monitor the treatment. The reticulocyte hemoglobin equivalent (RET-He), recently introduced to determine the Forward Scatter of Fluorescence-labeled Reticulocytes, seems to be a sensitive indicator of Iron-deficiency anaemia. Ret-He is effective for distinguishing Iron deficiency from anaemia of chronic disease and the combined state of functional ID/ACD.

New Reticulocyte parameters like Ret-He are excellent tools to assess various states of Iron deficiency in situations where the classical serum parameters fail or are too expensive i.e. when inflammation or cancer are present, in patients on chronic hemodialysis or for screening for Iron deficiency in toddlers.

The dedicated body fluid mode allows for rapid and standardised automated evaluation of various body fluids directly from the sample tube, and provides differentials for mononuclear and polymorphonuclear leukocytes to aid interpretations. The analyzer provides extremely reliable counts even at low concentrations, thus enhancing user confidence. With the Sysmex XT4000i, Transasia is looking to enable the diagnostic laboratories and hospital labs to provide advanced clinically relevant information to optimise patient care.

Contact:
Transasia Bio-Medicals Ltd
Transasia House, 8 Chandivali Studio Road, Andheri (E), Mumbai - 400 072
Tel: (022) 40309000, Fax: (022) 2857 3030 Email: transasia@transasia.co.in

 


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