From algorithm to bedside: What must happen before AI can be trusted in patient care

Dr Meera Santosh, Convenor, TIS-H Clinical AI Summit 2026 and Consultant Anaesthesiologist, Gleneagles Hospital Mumbai, talks about what it will take to move AI from promising algorithms and pilots to safe, reliable and clinically useful tools at the bedside

As healthcare AI moves from promising pilots to real clinical environments, the challenge now is to build evidence, safety, governance and deployment pathways that clinicians and hospitals can trust.

Artificial intelligence is steadily becoming part of healthcare. We see it in radiology, pathology, critical care, clinical documentation and hospital operations. Some tools are already useful. Many more are showing promise. But as a clinician, the question that matters to me is not simply whether an algorithm can perform a task. The real question is whether I can trust its output enough to use it while making a decision for a patient.

That is where the conversation on healthcare AI needs to move now. A good pilot or an impressive accuracy number is important, but it is not the same as clinical readiness. There is still a long journey between a model that works in development and a tool that can safely become part of everyday patient care.

Technical performance is only the beginning

In clinical practice, the patient in front of us is rarely the patient an algorithm was trained on. Patients come with multiple illnesses, incomplete histories, changing physiology and circumstances that do not fit neatly into a dataset. Clinical decisions are also rarely based on one finding. We combine examination, investigations, previous history, response to treatment and clinical judgement, often under time pressure.

So when an AI tool reports a result, we need to know more than how well it performed during development. Has it been tested in patients similar to ours? Does it perform consistently in the setting where it will actually be used? Where does it fail? Are there groups in whom it performs differently? Most importantly, does the information it provides help the clinician make a better or safer decision? That is the level at which clinical validation has to happen.

Clinicians have to be involved much earlier

One issue I see repeatedly in healthcare AI is that clinicians are sometimes brought into the conversation after the product has already been built. We are then asked to test it, validate it or use it. I believe that sequence needs to change. The starting point should be a clinical problem, not technology looking for an application.

Clinicians know where decisions become difficult, where workflows break down, what information is genuinely useful and what simply creates another alert on an already crowded screen. Their role should not be limited to being end users. They need to be involved in defining the problem, deciding what a useful output would look like, questioning the result, participating in validation and helping determine how the technology should fit into patient care.

Deployment is where the harder work begins

Building the algorithm may be the technical part. Getting it safely into patient care is where the harder work begins. A tool can work well during a pilot and still fail in routine practice. It may sit outside the hospital workflow, require clinicians to move between systems, produce information at the wrong point in care or add work instead of reducing it.

Hospitals therefore have to look beyond the model itself. Can it integrate with existing systems? Who is expected to act on its output? What happens when the technology is unavailable? What happens when the AI output and the clinician’s assessment do not agree? Who trains the users, monitors performance and takes responsibility for ongoing support? These may sound like implementation questions, but in healthcare they are also patient safety questions.

Trust also needs governance

The closer AI gets to patient care, the more important governance becomes. These systems can work with sensitive patient information and, in some situations, influence clinical decisions. Hospitals need clarity about what data is being used, where it is stored, who has access to it and what the intended role of the AI system actually is.

Accountability also has to remain clear. AI may support a decision, but it cannot create ambiguity about who is responsible for patient care. Privacy, transparency, data protection and oversight should be considered before deployment, not added later as a compliance exercise. Good governance does not slow responsible innovation. It gives clinicians and institutions greater confidence to use it.

A successful pilot is not the finish line

Healthcare has no shortage of pilots. The more difficult question is what happens after a pilot works. Can the solution move into routine use? Can another department use it? Can the hospital justify continuing to pay for it? Is it actually improving an outcome that matters?

That outcome will be different for different technologies. It may be diagnostic accuracy, turnaround time, patient safety, clinician workload, resource use or quality of care. But it has to be visible and measurable. We also need to keep watching the tool after deployment because patient populations, workflows and data change. An AI system that performed well at the time of implementation cannot simply be assumed to remain useful forever.

The real test is at the bedside

For me, this is ultimately a very simple test. Can I trust this tool enough to use its output while making a decision for my patient? Everything between algorithm development and bedside deployment should help us answer that question.

India needs healthcare innovation, and there is enormous potential for AI to improve the way we diagnose, treat and deliver care. But innovation alone is not the endpoint. We need clearer pathways to take useful technologies through clinical validation, hospital deployment, governance and continued monitoring. If we can build those pathways well, we will move beyond impressive demonstrations and isolated pilots towards AI that clinicians can actually use, hospitals can responsibly adopt and patients can benefit from.

artificial intelligence (AI)digital healthHealthcaretechnology
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