Fuji 3D synapse technology proves critical for early TB detection in kidney transplant screening

The authors highlight how advanced 3D navigational imaging supports early TB detection in kidney transplant evaluations

For most individuals awaiting a kidney transplant, the months leading up to surgery are filled with preparation and anticipation. For some, however, previously undetected health problems can suddenly change the course of their treatment. We should know that infections like tuberculosis (TB), if overlooked, can silently place transplant patients at great risk. While TB is treatable, in someone with kidney failure who is about to undergo immune-suppressing therapy, it can quickly become life-threatening. 

In these conditions, sophisticated techniques such peripheral pulmonary nodule biopsy using Fuji Synapse 3D software (navigational software), radial probe (RP) EBUS, and fluoroscopy is essential. These technologies enhance patient safety and guarantee prompt diagnosis by accurately identifying and sampling hard-to-reach lung lesions.

Why is early recognition important?

To prevent rejection of the new organ, kidney transplant recipients need to take strong medications like steroids. By weakening the immune system, these drugs expose the body to concealed diseases. If TB is not detected and treated before surgery, it can spread quickly once immunity is compromised, often depleting the body and leading to potentially deadly outcomes.

Therefore, routine pre-operative exams are more than just a formality; they are essential safeguards. They guarantee that individuals are healthy enough to undergo transplantation and that hidden dangers, such as infections or lung nodules, are not overlooked.

Signs patients should be alert to

Even though tuberculosis can occasionally be quiet, people and families should be mindful of the following early warning signs: 

  • A persistent cough that lasts longer than two to three weeks;
  • Night sweats or unexplained weight loss;
  • Recurrent low-grade fever 
  • Shortness of breath or chest discomfort; 
  • fatigue beyond the typical weariness associated with renal failure 

These symptoms may worsen if left untreated, particularly following a transplant when the body’s immune is purposefully weakened.

Mr. Krishna Mohan’s fight against the unexpected

At 52, Mr. Krishna Mohan had already endured years of diabetes, high blood pressure, and dialysis. Finally, he was preparing for a kidney transplant that would change his life. He felt ready, mentally and physically.

As doctors performed a chest CT scan during a routine pre-surgery evaluation, it revealed something unexpected which was a small nodule in his right lung. Though he had no cough, fever, or chest discomfort, the finding could not be dismissed.

Reaching the nodule for a biopsy proved difficult. Instead of traditional procedures, surgeons used the sophisticated Peripheral Pulmonary nodule biopsy using Fuji-3D Synapse navigation software, which is similar to a navigational software. It created a 3D map of his chest, directing specialists to the best area for a safe and precise biopsy. As the treatment lasted less than an hour as the procedure was minimally invasive. He was relieved to hear that he will be freed that evening. 

As the results were processed the news was mixed, but ultimately life-saving. The nodule was not malignant, but it did contain TB.

The turning point

Detecting TB before the transplant was crucial. Left untreated, the post-surgical medications would have allowed the infection to flare uncontrollably. As we explained, “catching it now has made all the difference.”

With TB treatment promptly started, Mr. Mohan’s path to a transplant became safer. His family described the discovery as a “blessing in disguise”, what first seemed like a setback had, in fact, protected his chance at survival.

What patients and families should know

For anyone preparing for major surgery, especially a transplant, awareness and vigilance can make a critical difference:

  • Routine examinations are essential since even little findings might have an effect on results.
  • Prior to a donation, early diagnosis of illnesses like TB is essential.
  • Regardless of how well you feel, always go to pre-surgery assessments.
  • Recognise danger signs include weight loss, an inexplicable fever, and a persistent cough. 
  • The safety and effectiveness of early detection are increased when minimally invasive technology is used. 

An optimistic outcome

These kinds of stories bring to light an even deeper truth: life-saving discoveries might come as a surprise. Routine tests, sensitivity to hidden symptoms, and early medical testing may all make a difference in being prepared for a major treatment, particularly a transplant. 

Even while TB and other illnesses may not often display evident symptoms, they can be efficiently treated if detected early. Multidisciplinary treatment and new technology can help to manage even the most difficult medical situations more successfully. The community’s message is clear: the easiest and most efficient ways to preserve our health are to be watchful, pay attention to little changes in our health, and seek medical assistance as soon as possible.

early TB detectionFuji 3D Synapsekidney transplant screeningManipal Hospital Yeshwanthpurperipheral pulmonary nodule biopsy
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