Genefitletics introduces Agegorithm to measure biological age at the molecular level

Genefitletics has launched Agegorithm, a machine learning-based human biology model that quantifies biological processes at the molecular and cellular level to measure biological age. The model evaluates the efficiency of gut and oral microbiome functions, as well as mitochondrial activity, to determine how an individual is aging at the cellular level in comparison to their chronological age.

The company states that Agegorithm is built on a mathematical algorithm that is entirely data-driven and developed using six billion molecular data points, phenotype metadata, and longitudinal data specific to the Indian adult population within the age range of 18 to 55 years. The company’s machine learning platform, PROTEBA, runs the algorithm to analyse molecular activity and mitochondrial efficiency, enabling it to assign a numerical value to biological age.

The model integrates more than 400 biochemical pathways and considers multiple health parameters, including oral health, immune system health, heart and metabolic health, energy efficiency, gut health, and stress response. The analysis identifies the sources of systemic inflammation and oxidative stress that contribute to accelerated aging. These insights are integrated into the company’s proprietary recommendation engine to design personalised nutritional therapeutics, supplements, and oral hygiene interventions aimed at optimising biochemical functions to improve biological age.

This biological age feature is integrated with the company’s full-body biochemistry solution, ORAHYG PRO, and is available at no additional cost.

Sushant Kumar, Founder and CEO of Genefitletics, stated, “With biohacking taking a prominent place in the Indian healthcare system, there is an urgent need to go beyond measuring telomere length, blood works, and DNA methylation techniques, and focus on measuring biology at the molecular and cellular level to reverse the biological age clock.” He emphasised the role of the oral and gut microbiome, along with cellular functions, in optimising health and longevity.

Genefitletics, a consumer biotech and longevity company founded in 2020, offers PROTEBA, a systems biology platform that collects, processes, and analyses molecular and phenotype metadata. The platform applies mathematical models to detect biochemical changes at the cellular level before diseases manifest or in their earliest stages, enabling disease-modifiable therapeutic interventions. It translates 10 million molecular data points from an individual’s biological sample into more than 400 molecular pathways, allowing precise identification of nutrient or substrate requirements to restore cellular homeostasis.

The company also provides BIACCESS, a separate platform for healthcare practitioners. This platform grants doctors access to molecular signatures that are not detectable by conventional diagnostic tests, supporting precision in treatment approaches.