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Owkin and Amgen use AI to improve cardiovascular risk prediction

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Using data from 13,756 patients who were part of FOURIER, a large Amgen clinical trial, Owkin trained a machine-learning algorithm to predict those at higher risk of cardiovascular events

AI startup Owkin and Amgen have announced the results of a three-year project to use artificial intelligence to more accurately predict cardiovascular risk. This study demonstrates the ability of AI to improve the way that clinicians predict patients’ risk of suffering major cardiovascular events, such as strokes and myocardial infarctions.

Using data from 13,756 patients who were part of FOURIER, a large Amgen clinical trial, Owkin trained a machine-learning algorithm to predict those at higher risk of cardiovascular events. Published in the upcoming December issue of the European Heart Journal – Digital Health, the results show that machine learning is more efficient and effective than the statistical models routinely used by clinicians.

By improving the ability to predict cardiovascular events, clinicians are better able to prevent them. Identifying at-risk patients sooner will allow them to benefit from better care, adapted to their individual risk profile. Thus, identified patients will benefit from better follow-up and therapeutic management adapted to their risk level. With electronic medical records being more complete and prevalent than ever before, the use of machine learning to better predict cardiovascular risk could have wide application.

For five years, Owkin and Amgen have been collaborating on projects across cardiology, hematology and oncology to develop clinical applications for artificial intelligence. Last month, Owkin became a ‘unicorn’ – a startup valued at over $1 billion – through a $180 million investment from Sanofi, which was announced alongside $90 million of joint cancer research projects.

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